Michael A GONZALEZ 
BMedSci, BMBS (Nottingham), PhD (Cambridge), MRCP(UK) 

Fellow since 2008

JB & Millicent Kaye Prize Research Fellow

Email: mg322 "at" cam.ac.uk

I am a Clinician Scientist at the MRC Cancer Cell Unit and Honorary Specialist Registrar in Medical Oncology at Addenbrooke's Hospital. My research focuses on the control of DNA replication and its scope for clinical exploitation.  I am specifically interested in proteins that restrict DNA replication to once per cell cycle and how these might be abnormally regulated in the cancer cell.  Such proteins are emerging as useful biomarkers that can be used for the early detection of cancer, as well as for the accurate estimation of prognosis and assessment of response to treatment for a range of cancer types.  I am also interested in the discovery of novel drug candidates. Proteins that control the initiation of DNA replication may represent effective targets for inhibiting cancer cell proliferation.

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